Articles

Title:	Effect of two different Nodularia spumigena extracts on Danio rerio egg mortality and hatching time
Authors:	Pliński Marcin Mazur-Marzec Hanna Tymińska Anna Graczyk Monika
Abstract:	Every summer the coastal area of the Gulf of Gdansk is affected by intensive blooms of Nodularia spumigena. This cyanobacterium produces nodularin (NOD), hepatotoxic pentapeptide containing a unique amino acid residue – Adda. There is strong evidence that nodularin can cause liver damage in mammals and fish and promote liver cancer. Some incidents of dog, duck, cattle and fish death attributed to N. spumigena bloom have been reported. In our work, bloom samples of toxic Nodulariawere collected and extracts were prepared with two solvents of different polarity. In laboratory experiment the effect of the extracts on a small tropical cyprinid Danio rerio, was investigated. The results showed that methanol extract had more pronounced effect on eggs and larvae development. Increased egg mortality, earlier hatching and malformations of larvae were observed. The different activity of the two extracts, containing equal amounts of nodularin, seemed to support the hypothesis that it is not nodularin, but probably other Nodularia cell components, that are responsible for the observed changes in Danio development.
DOI:
Type of paper:	Original research paper
Pages:	149 to 159
Cytation:	Tymińska A., Mazur-Marzec H., Graczyk M., Pliński M., 2005, Effect of two different Nodularia spumigena extracts on Danio rerio egg mortality and hatching time, Ocean. Hydrob. Studies, 34(Supl.3): 149-159
Keywords:	Nodularia spumigena, nodularin, toxicity, Danio rerio
Year:	2005
Category:
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